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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TP53RK
All Species:
16.36
Human Site:
Y125
Identified Species:
32.73
UniProt:
Q96S44
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96S44
NP_291028.3
253
28160
Y125
G
S
V
T
V
R
D
Y
I
Q
S
T
M
E
T
Chimpanzee
Pan troglodytes
XP_514697
253
28128
Y125
G
S
V
T
V
R
D
Y
I
Q
S
T
M
E
T
Rhesus Macaque
Macaca mulatta
XP_001107480
201
22218
L90
T
P
Q
S
L
S
N
L
A
K
T
I
G
Q
V
Dog
Lupus familis
XP_853966
302
33650
Y174
G
S
V
T
V
R
D
Y
I
Q
S
T
M
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99PW4
244
27375
Y116
D
S
V
T
V
R
D
Y
I
Q
S
T
M
E
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425703
314
33606
H186
G
A
I
A
V
Q
D
H
I
Y
S
V
Q
R
S
Frog
Xenopus laevis
NP_001089506
237
26742
Y109
E
S
T
T
V
R
D
Y
I
L
S
M
Q
Q
S
Zebra Danio
Brachydanio rerio
NP_001018386
231
26056
H107
N
S
V
S
V
R
D
H
I
R
S
Q
P
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647948
224
25346
E102
E
T
V
S
T
Q
T
E
D
E
A
K
K
C
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002300825
226
25241
F101
G
P
S
V
K
D
I
F
L
E
F
G
L
N
G
Maize
Zea mays
NP_001146448
226
25230
L101
G
L
S
V
K
D
I
L
L
R
F
G
S
D
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53323
261
29918
F125
G
F
S
N
L
K
N
F
L
W
M
H
D
Q
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
68.3
78.4
N.A.
83.7
N.A.
N.A.
N.A.
56.3
66
61.2
N.A.
41.5
N.A.
N.A.
N.A.
Protein Similarity:
100
100
71.9
81.1
N.A.
88.9
N.A.
N.A.
N.A.
66.2
78.2
77.4
N.A.
56.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
93.3
N.A.
N.A.
N.A.
33.3
53.3
46.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
40
100
N.A.
93.3
N.A.
N.A.
N.A.
66.6
66.6
73.3
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
44.2
41.9
N.A.
N.A.
32.1
N.A.
Protein Similarity:
60.4
58.1
N.A.
N.A.
48.6
N.A.
P-Site Identity:
6.6
6.6
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
33.3
26.6
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
0
0
0
9
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
9
0
0
0
0
17
59
0
9
0
0
0
9
17
9
% D
% Glu:
17
0
0
0
0
0
0
9
0
17
0
0
0
34
0
% E
% Phe:
0
9
0
0
0
0
0
17
0
0
17
0
0
0
0
% F
% Gly:
59
0
0
0
0
0
0
0
0
0
0
17
9
0
25
% G
% His:
0
0
0
0
0
0
0
17
0
0
0
9
0
0
0
% H
% Ile:
0
0
9
0
0
0
17
0
59
0
0
9
0
0
0
% I
% Lys:
0
0
0
0
17
9
0
0
0
9
0
9
9
0
0
% K
% Leu:
0
9
0
0
17
0
0
17
25
9
0
0
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
9
34
0
0
% M
% Asn:
9
0
0
9
0
0
17
0
0
0
0
0
0
9
0
% N
% Pro:
0
17
0
0
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
9
0
0
17
0
0
0
34
0
9
17
25
0
% Q
% Arg:
0
0
0
0
0
50
0
0
0
17
0
0
0
9
0
% R
% Ser:
0
50
25
25
0
9
0
0
0
0
59
0
9
0
17
% S
% Thr:
9
9
9
42
9
0
9
0
0
0
9
34
0
0
34
% T
% Val:
0
0
50
17
59
0
0
0
0
0
0
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
42
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _